Drugs/Medications contraindicated with Ayahuasca
It is strongly suggested not to combine pharmaceutical drugs and medications (including some over-the-counter drugs and certain herbs) with Ayahuasca.
Unlike food interaction which can be unlikely serious, interaction with drugs can be potentially life-threatening.
Below is a list of contraindicated drugs. If you have any questions please do not hesitate to contact us directly.
A list of meds to be careful of with MAOIs:
- other MAOIs
- SSRI’s (any selective serotonin reuptake inhibitor)
- amphetamines (meth-, dex-, amphetamine)
- antihypertensives (high blood pressure medicine)
- appetite suppressants (diet pills)
- medicine for asthma, bronchitis, or other breathing problems
- antihistamines, medicines for colds, sinus problems, hay fever, or allergies (Actifed DM, Benadryl, Benylin, Chlor-Trimeton, Compoz, etc.)
- CNS (central nervous system) depressants
Some specific drugs that should not be combined with MAOIs:
- Amantadine hydrochloride (Symmetrel)
- Amoxapine (Asendin)
- Bupropion (Wellbutrin)
- Buspirone (BuSpar)
- Carbamazepine (Tegretol, Epitol)
- Clomipramine (Anafranil)
- Cyclobenzaprine (Flexeril)
- Cyclizine (Marezine)
- Desipramine (Pertofrane)
- Dextromethorphan (DXM)
- Disopyramide (Norpace)
- Doxepin (Sinequan)
- Flavoxate Hydrochloride (Urispas)
- Fluoxetine (Prozac)
- Imipramine (Tofranil)
- Isocarboxazid (Marplan)
- Levodopa (Dopar, Larodopa)
- Loratadine (Claritin)
- Maprotiline (Ludiomil)
- Meperidine (Demerol)
- Methylphenidate (Ritalin)
- Nortriptyline (Aventyl)
- Oxybutynin chloride (Ditropan)
- Orphenadrine (Norflex)
- Paroxetine (Paxil)
- Phenelzine (Nardil)
- Procainamide (Pronestyl)
- Protriptyline (Vivactil)
- Quinidine (Quinidex)
- Selegiline (Eldepryl)
- Sertraline (Zoloft)
- Tranylcypromine (Parnate)
- Tricyclic antidepressants (Amitriptyline, Elavil)
- Trimipramine (Surmontil)
Also avoid the following herbs:
- St. Johns Wort
Using Tricyclic antidepressants within two weeks of taking MAOIs may cause serious side effects including sudden fever, extremely high blood pressure, convulsions, and death.
Using Fluoxetine (Prozac) within five weeks of taking MAOIs may cause high fever, rigidity, high blood pressure, mental changes, confusion and hypomania.
Using Meperidine (Demerol) with pharmaceutical MAOIs has resulted in deaths from a single dose.
Using cocaine with MAOIs may cause a severe increase in blood pressure, increasing the chances for stroke and cerebral hemorrhage and making it possible to overdose on a relatively small amount of cocaine. (A fatality has been recorded involving combining Peganum harmala and cocaine.)
Using Bupropion (Wellbutrin) within two weeks of taking MAOIs may cause serious side effects such as seizures.
Using Buspirone (Buspar) with MAOIs may cause high blood pressure.
Using Carbamazepine (Tegretol) with MAOIs may increase seizures.
Using CNS depressants with MAOIs may increase the depressant effects.
Using Dextromethorphan with MAOIs may cause excitement, high blood pressure, and fever, or brief episodes of psychosis.
Using Tryptophan with MAOIs may cause disorientation, confusion, amnesia, delirium agitation, hypomanic signs, shivering.
Using alcohol with MAOIs may cause side effects like angina (chest pain) or headaches. The headache may mask or be mistaken for hypertensive crisis caused by MAOI interaction.
Using Kava with MAOIs may result in hypotensive crisis (severe blood pressure drop).
Using Temaril with MAOIs may increase chance of side effects.